On a flight to Mumbai, Akshay meets with his wealthy ex-girlfriend, Sanjana, who is in the company of another male, Rajeev. He, a struggling artist, recalls how he met her in Cape Town and their moving in together. Differences crop up, and get worse, when he does not meet with her busy dad, leading to their taking different paths. After the plane lands they head out to their respective destinations - little knowing the danger that awaits them after the city experiences life-threatening heavy rains and floods.

Agneepath is a story of revenge of Vijay Chauhan against an evil and sadistic Kaancha, who hangs Vijay's father to death. Vijay grows up with a single aim of avenging his father's death. The story revolves around Vijay Chauhan, his relationships with his family and above all, his Revenge.